Pevisone Cream

✔️ Uses of Pevisone Cream:

• Fungal Infections
• Skin Infections

✔️ How to use Pevisone Cream:

Just apply this medicine to your skin. Clean and thoroughly dry the treatment area. Apply this medicine to the afflicted region and around it as instructed by your doctor, generally once or twice a day. The duration and amount of treatment are determined by the type of infection being treated. Do not use this drug more frequently or for a longer period of time than suggested.

Unless the area being treated involves the hands, wash your hands after use. Wrap, cover, or bandage the affected area only if instructed to do so by your doctor.

This drug should not be used in the eyes, nose, mouth, or within the vagina. If you receive the medication in certain places, rinse well with water.

✔️ Side effects of Pevisone Cream:

• Mild Irritation
• Redness at the application site
• Itching
• Burning
• Stinging

✔️ Indications of Pevisone Cream:

Atopic dermatitis, contact dermatitis, eczematous dermatitis, neurodermatitis, seborrheic dermatitis, insect bites, lichen simplex chronicus, exfoliative dermatitis, stasis dermatitis, nummular eczema, psoriasis, and pruritus ani and vulvae are all treated with it.

✔️ Pharmacology of Pevisone Cream:

Econazole Nitrate: Econazole alters the permeability of the cell wall membrane in fungi; it may also affect lipid metabolism and RNA and protein synthesis. The primary action of Pevisone Creamis a glucocorticoid. It lessens capillary permeability and slows the movement of polymorphonuclear leukocytes, hence reducing inflammation.

✔️ Dosage of Pevisone Cream:

• Adults: Apply twice daily to the affected area and rub on the skin gently with the finger. Continue the applications for 14 days or as directed by the doctor.
• Children: Suitable for topical application to children.
  For topical administration only.

✔️ Administration of Pevisone Cream:

• 1-2 times per day, a small amount of Pevisone Cream is gently rubbed into the affected area. Pevisone Cream applied under an occlusive dressing may be more effective in treating some cases of eczematoid psoriasis.
• Technique for occlusive dressing: Gently rub a small amount of Pevisone Cream on the lesion until it disappears. Reapply, leaving a thin coating, and then cover with a pliable non-porous film. Apply Pevisone Cream intermittently (12-hour occlusion during the night) followed by reapplication without occlusion during the day for convenience.
• Pevisone Cream should not be used in children under the age of eight. Topical corticosteroids should be administered to children in the smallest amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may impair children's growth and development. Children should not be treated for more than 5 days because they are more likely to experience side effects.

✔️ Interaction of Pevisone Cream:

The CYP3A4/2C9 enzyme breaks down the oral anticoagulant econazole to its active form. Salicylate levels in the blood are decreased by triamcinolone. NSAIDs raise the possibility of ulceration and bleeding in the Gl. obstructed the blood glucose-lowering effects of the antidiabetic. The risk of hyperkalemia is raised by beta-blockers, amphotericin B, potassium-depleting diuretics, and theophylline. Triamcinolone clearance is boosted by the use of ciclosporin, carbamazepine, phenytoin, barbiturate, and rifampicin.

✔️ Contraindications of Pevisone Cream:

• It is not recommended for use by anybody with known allergies to any of the ingredients in this cream.
• This Cream is contraindicated in cases of specific skin conditions, including tuberculosis, varicella, herpes simplex, or other viral skin infections, as well as fresh vaccination sites, just like any other dermatological preparation containing corticosteroids.
• Skin conditions known as decubitus ulcers are brought on by bacteria, fungi, or viruses (e.g. tuberculosis of the skin, syphilis of the skin, herpes simplex, herpes zoster, chickenpox).
• Two different kinds of rosacea are rosacea and rosacea-like dermatitis.

✔️ Pregnancy & Lactation:

Pregnancy: Because Econazole does not cross the placenta as Triamcinolone Acetonide does, topical corticosteroids during pregnancy may cause issues with the development of the fetus. It is yet unclear whether this discovery applies to people. It is not advised to use topical steroids during pregnancy, especially not in high doses or for extended periods of time.

Econazole and Triamcinolone, in smaller amounts, are secreted in breast milk during lactation. As a result, lactation should be discontinued during treatment if this cream is administered to a nursing mother.

✔️ Precautions & Warnings of Pevisone Cream:

• Only for use on the outside.
• This cream should not be used on the eyes or in the mouth.
• If a reaction indicating hypersensitivity or chemical irritation occurs, the drug should be discontinued immediately.
• Corticosteroids applied to the skin can be absorbed in sufficient amounts to cause systemic effects such as adrenal suppression.
• Treatment across a broad skin surface area, application to injured skin, administration beneath occlusive skin dressings, and prolonged therapy duration may all improve systemic absorption.
• Children: When treating children, extra caution is required. The nature of a child's skin, as well as a larger skin surface area relative to body weight, may contribute to increased corticosteroid absorption through the skin. This cream should only be used on small areas.

✔️ Storage Conditions of Pevisone Cream:

Store away from light in a cold (below 30°C) and dry location. Keep out of children's reach.